Why mini IVF is better than traditional IVF for low AMH

You may be a good candidate for mini IVF if you are considered to have low ovarian reserve – meaning your ovaries have a relatively low number of eggs. If you have a low AMH of <1, an elevated FSH >9, and a low Antral Follicle Count (AFC), you may be considered to have Diminished Ovarian Reserve (DOR) and you would benefit from a mini IVF protocol over traditional IVF.

If you have low AMH and are considered to be in the “category” of DOR, you can absolutely still have success with mini IVF if you are still cycling regularly.

The reason why a mini IVF protocol is preferable over traditional high-dose IVF is because higher doses of follicle-stimulating medications can actually overwhelm the fewer follicles that are available, causing them to either grow asynchronously (at different rates) and do not mature properly, often leading to a cancelled cycle.

The lower doses of medication used in mini IVF helps the ovaries produce higher quality eggs with less of a chance of negative side effects like Ovarian Hyper Stimulation Syndrome (OHSS). Mini IVF also has the added benefit of being significantly less expensive since lower doses of the medications are used.